纳洛酮
TL;DR: 纳洛酮 (CAS 1261079-38-2) is a chemical compound with molecular formula C19H21NO4 and molecular weight 327.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
纳洛酮
4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Also Known As: naloxone, Naloxone D5, l-Naloxone, Naloxone(-), (-)-Naloxone
| Molecular Formula | C19H21NO4 |
|---|---|
| Molecular Weight | 327.15 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 70.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 327.14706 |
| Heavy Atoms | 24 |
| Complexity | 594.0 |
Chemical Identifiers
| CAS Number | 1261079-38-2 |
|---|---|
| SMILES | C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O |
| InChIKey | UZHSEJADLWPNLE-UHFFFAOYSA-N |
Product Overview
纳洛酮 (CAS 1261079-38-2), with molecular formula C19H21NO4 and molecular weight 327.15 g/mol. IUPAC: 4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.
Chemical Property Profile of 纳洛酮
Property Insights of 纳洛酮
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 纳洛酮. The TPSA of 70.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 纳洛酮. Following Lipinski's Rule of Five, naloxone has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of naloxone?
The CAS number of naloxone is 1261079-38-2.
What is the molecular formula of naloxone?
The molecular formula of naloxone is C19H21NO4.
What is the molecular weight of naloxone?
The molecular weight of naloxone is 327.15 g/mol.
Where can I buy naloxone?
You can request a quote for naloxone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for naloxone?
Yes, KEHONG BIO provides custom synthesis services for naloxone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.