Amsilarotene
TL;DR: Amsilarotene (CAS 125973-56-0) is a chemical compound with molecular formula C20H27NO3Si2 and molecular weight 385.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[[3,5-bis(trimethylsilyl)benzoyl]amino]benzoic acid
Also Known As: Amsilarotene, amsilaroteno, amsilarotenum, Amsilarotene [INN], Am-555S
| Molecular Formula | C20H27NO3Si2 |
|---|---|
| Molecular Weight | 385.15 g/mol |
| LogP | 3.7275 |
| Topological Polar Surface Area | 66.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 385.15295 |
| Heavy Atoms | 26 |
| Complexity | 799.3653 |
Chemical Identifiers
| CAS Number | 125973-56-0 |
|---|---|
| SMILES | C[Si](C)(C)C1=CC(=CC(=C1)C(=O)NC2=CC=C(C=C2)C(=O)O)[Si](C)(C)C |
Product Overview
Amsilarotene (CAS 125973-56-0), with molecular formula C20H27NO3Si2 and molecular weight 385.15 g/mol. IUPAC: 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]benzoic acid.
Chemical Property Profile of Amsilarotene
Property Insights of Amsilarotene
The XLogP value of 3.7275 indicates that Amsilarotene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Amsilarotene. Following Lipinski's Rule of Five, Amsilarotene has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amsilarotene?
The CAS number of Amsilarotene is 125973-56-0.
What is the molecular formula of Amsilarotene?
The molecular formula of Amsilarotene is C20H27NO3Si2.
What is the molecular weight of Amsilarotene?
The molecular weight of Amsilarotene is 385.15 g/mol.
Where can I buy Amsilarotene?
You can request a quote for Amsilarotene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amsilarotene?
Yes, KEHONG BIO provides custom synthesis services for Amsilarotene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.