5'-Isoleucyl 3'-azido-3'-deoxythymidine
TL;DR: 5'-Isoleucyl 3'-azido-3'-deoxythymidine (CAS 125780-95-2) is a chemical compound with molecular formula C16H24N6O5 and molecular weight 380.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (2S,3S)-2-amino-3-methylpentanoate
Also Known As: IAZT, Isoleucinyl-AZT, 5'-Isoleucyl 3'-azido-3'-deoxythymidine, 5/'-isoleucyl 3/'-azido-3/'-deoxythymidine, 5'-L-Isoleucinyl-3'-azido-3'-deoxythymidine
| Molecular Formula | C16H24N6O5 |
|---|---|
| Molecular Weight | 380.18 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 125.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 380.18082 |
| Heavy Atoms | 27 |
| Complexity | 689.0 |
Chemical Identifiers
| CAS Number | 125780-95-2 |
|---|---|
| SMILES | CC[C@H](C)[C@@H](C(=O)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)N=[N+]=[N-])N |
| InChIKey | QUANSGVUESEHKX-FXAPSIEYSA-N |
Product Overview
5'-Isoleucyl 3'-azido-3'-deoxythymidine (CAS 125780-95-2), with molecular formula C16H24N6O5 and molecular weight 380.18 g/mol. IUPAC: [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (2S,3S)-2-amino-3-methylpentanoate.
Chemical Property Profile of 5'-Isoleucyl 3'-azido-3'-deoxythymidine
Property Insights of 5'-Isoleucyl 3'-azido-3'-deoxythymidine
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5'-Isoleucyl 3'-azido-3'-deoxythymidine. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 5'-Isoleucyl 3'-azido-3'-deoxythymidine. Following Lipinski's Rule of Five, 5'-Isoleucyl 3'-azido-3'-deoxythymidine has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5'-Isoleucyl 3'-azido-3'-deoxythymidine?
The CAS number of 5'-Isoleucyl 3'-azido-3'-deoxythymidine is 125780-95-2.
What is the molecular formula of 5'-Isoleucyl 3'-azido-3'-deoxythymidine?
The molecular formula of 5'-Isoleucyl 3'-azido-3'-deoxythymidine is C16H24N6O5.
What is the molecular weight of 5'-Isoleucyl 3'-azido-3'-deoxythymidine?
The molecular weight of 5'-Isoleucyl 3'-azido-3'-deoxythymidine is 380.18 g/mol.
Where can I buy 5'-Isoleucyl 3'-azido-3'-deoxythymidine?
You can request a quote for 5'-Isoleucyl 3'-azido-3'-deoxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5'-Isoleucyl 3'-azido-3'-deoxythymidine?
Yes, KEHONG BIO provides custom synthesis services for 5'-Isoleucyl 3'-azido-3'-deoxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.