3'-Azido-5'-glutamyl-3'-deoxythymidine
TL;DR: 3'-Azido-5'-glutamyl-3'-deoxythymidine (CAS 125780-86-1) is a chemical compound with molecular formula C15H20N6O7 and molecular weight 396.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid
Also Known As: GluAZT, 3'-Azido-5'-glutamyl-3'-deoxythymidine, L-Glutamic acid, 5.5'-ester with 3'-azido-3'-deoxythymidine, (4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid, 3 -Azido-3 -deoxy-5 -O-[(2S)-2-amino-4-carboxybutyryl]thymidine
| Molecular Formula | C15H20N6O7 |
|---|---|
| Molecular Weight | 396.14 g/mol |
| LogP | -2.7 |
| Topological Polar Surface Area | 163.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 9 |
| Exact Mass | 396.13934 |
| Heavy Atoms | 28 |
| Complexity | 747.0 |
Chemical Identifiers
| CAS Number | 125780-86-1 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(=O)[C@H](CCC(=O)O)N)N=[N+]=[N-] |
| InChIKey | RDUNYDIEPCWJHF-UKKRHICBSA-N |
Product Overview
3'-Azido-5'-glutamyl-3'-deoxythymidine (CAS 125780-86-1), with molecular formula C15H20N6O7 and molecular weight 396.14 g/mol. IUPAC: (4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid.
Chemical Property Profile of 3'-Azido-5'-glutamyl-3'-deoxythymidine
Property Insights of 3'-Azido-5'-glutamyl-3'-deoxythymidine
The XLogP value of -2.7 indicates that 3'-Azido-5'-glutamyl-3'-deoxythymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 163.0 Ų indicates high polarity, suggesting 3'-Azido-5'-glutamyl-3'-deoxythymidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3'-Azido-5'-glutamyl-3'-deoxythymidine has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Azido-5'-glutamyl-3'-deoxythymidine?
The CAS number of 3'-Azido-5'-glutamyl-3'-deoxythymidine is 125780-86-1.
What is the molecular formula of 3'-Azido-5'-glutamyl-3'-deoxythymidine?
The molecular formula of 3'-Azido-5'-glutamyl-3'-deoxythymidine is C15H20N6O7.
What is the molecular weight of 3'-Azido-5'-glutamyl-3'-deoxythymidine?
The molecular weight of 3'-Azido-5'-glutamyl-3'-deoxythymidine is 396.14 g/mol.
Where can I buy 3'-Azido-5'-glutamyl-3'-deoxythymidine?
You can request a quote for 3'-Azido-5'-glutamyl-3'-deoxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Azido-5'-glutamyl-3'-deoxythymidine?
Yes, KEHONG BIO provides custom synthesis services for 3'-Azido-5'-glutamyl-3'-deoxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.