Fluorodesloratadine
TL;DR: Fluorodesloratadine (CAS 125743-82-0) is a chemical compound with molecular formula C19H20ClFN2 and molecular weight 330.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
13-chloro-2-fluoro-2-piperidin-4-yl-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
Also Known As: 11-Fluoro Desloratadine, Fluorodesloratadine, Fluoro Desloratadine, Desloratadine EP Impurity A, Desloratadine Impurity A
| Molecular Formula | C19H20ClFN2 |
|---|---|
| Molecular Weight | 330.13 g/mol |
| LogP | 4.0463 |
| Topological Polar Surface Area | 24.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 330.1299 |
| Heavy Atoms | 23 |
| Complexity | 727.0596 |
Chemical Identifiers
| CAS Number | 125743-82-0 |
|---|---|
| SMILES | C1CNCCC1C2(C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)F |
Product Overview
Fluorodesloratadine (CAS 125743-82-0), with molecular formula C19H20ClFN2 and molecular weight 330.13 g/mol. IUPAC: 13-chloro-2-fluoro-2-piperidin-4-yl-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene.
Chemical Property Profile of Fluorodesloratadine
Property Insights of Fluorodesloratadine
The XLogP value of 4.0463 indicates that Fluorodesloratadine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.92 Ų, Fluorodesloratadine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Fluorodesloratadine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fluorodesloratadine?
The CAS number of Fluorodesloratadine is 125743-82-0.
What is the molecular formula of Fluorodesloratadine?
The molecular formula of Fluorodesloratadine is C19H20ClFN2.
What is the molecular weight of Fluorodesloratadine?
The molecular weight of Fluorodesloratadine is 330.13 g/mol.
Where can I buy Fluorodesloratadine?
You can request a quote for Fluorodesloratadine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fluorodesloratadine?
Yes, KEHONG BIO provides custom synthesis services for Fluorodesloratadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.