Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)
TL;DR: Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) (CAS 124930-62-7) is a chemical compound with molecular formula C11H16N5O6P and molecular weight 345.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-methylphosphinic acid
Also Known As: AZT-MeP, 3'-Deoxy-3'-azidothymidine-5'-methylphosphonate, Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate), 3'-Azido-3'-deoxy-5'-O-[hydroxy(methyl)phosphoryl]thymidine, [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-methyl-phosphinic acid
| Molecular Formula | C11H16N5O6P |
|---|---|
| Molecular Weight | 345.08 g/mol |
| LogP | -0.6 |
| Topological Polar Surface Area | 120.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 345.08383 |
| Heavy Atoms | 23 |
| Complexity | 645.0 |
Chemical Identifiers
| CAS Number | 124930-62-7 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(C)O)N=[N+]=[N-] |
| InChIKey | FFVDOSQCTCGNTB-DJLDLDEBSA-N |
Product Overview
Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) (CAS 124930-62-7), with molecular formula C11H16N5O6P and molecular weight 345.08 g/mol. IUPAC: [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-methylphosphinic acid.
Chemical Property Profile of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)
Property Insights of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)
The XLogP value of -0.6 indicates that Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 120.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate). Following Lipinski's Rule of Five, Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)?
The CAS number of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) is 124930-62-7.
What is the molecular formula of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)?
The molecular formula of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) is C11H16N5O6P.
What is the molecular weight of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)?
The molecular weight of Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) is 345.08 g/mol.
Where can I buy Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)?
You can request a quote for Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate)?
Yes, KEHONG BIO provides custom synthesis services for Thymidine, 3'-azido-3'-deoxy-, 5'-(hydrogen methylphosphonate) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.