KC 2846 structure

KC 2846

TL;DR: KC 2846 (CAS 124783-68-2) is a chemical compound with molecular formula C18H15BrFN3O and molecular weight 387.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2E)-2-[7-bromo-5-(2-fluorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-ylidene]acetamide

Also Known As: KC 2846, (2E)-2-[7-bromo-5-(2-fluorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-ylidene]acetamide, Acetamide, 2-(7-bromo-5-(2-fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-ylidene)-, (E)-, 2-[7-bromo-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-ylidene]acetamide, 7-Bromo-1-methyl-2-[(carbamoyl)methylene]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine

CAS: 124783-68-2
Molecular Formula C18H15BrFN3O
Molecular Weight 387.04 g/mol
LogP 3.2446
Topological Polar Surface Area 58.69 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 387.03824
Heavy Atoms 24
Complexity 876.3176

Chemical Identifiers

CAS Number 124783-68-2
SMILES CN1/C(=C/C(=O)N)/CN=C(C2=C1C=CC(=C2)Br)C3=CC=CC=C3F

Product Overview

KC 2846 (CAS 124783-68-2), with molecular formula C18H15BrFN3O and molecular weight 387.04 g/mol. IUPAC: (2E)-2-[7-bromo-5-(2-fluorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-ylidene]acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of KC 2846

XLogP
3.2446
TPSA (Topological Polar Surface Area)
58.69
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
24
Complexity
876.3176
Exact Mass
387.03824
Monoisotopic Mass
387.03824
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of KC 2846

The XLogP value of 3.2446 indicates that KC 2846 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.69 Ų, KC 2846 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, KC 2846 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of KC 2846?

The CAS number of KC 2846 is 124783-68-2.

What is the molecular formula of KC 2846?

The molecular formula of KC 2846 is C18H15BrFN3O.

What is the molecular weight of KC 2846?

The molecular weight of KC 2846 is 387.04 g/mol.

Where can I buy KC 2846?

You can request a quote for KC 2846 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for KC 2846?

Yes, KEHONG BIO provides custom synthesis services for KC 2846 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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