洛沙坦羧酸
TL;DR: 洛沙坦羧酸 (CAS 124750-92-1) is a chemical compound with molecular formula C22H21ClN6O2 and molecular weight 436.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛沙坦羧酸
2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
Also Known As: Losartan carboxylic acid, Carboxylosartan, EXP 3174, Losartancarboxylicacid, E-3174
| Molecular Formula | C22H21ClN6O2 |
|---|---|
| Molecular Weight | 436.14 g/mol |
| LogP | 5.0 |
| Topological Polar Surface Area | 110.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 436.14145 |
| Heavy Atoms | 31 |
| Complexity | 590.0 |
Chemical Identifiers
| CAS Number | 124750-92-1 |
|---|---|
| SMILES | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl |
| InChIKey | ZEUXAIYYDDCIRX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
洛沙坦羧酸 (CAS 124750-92-1), with molecular formula C22H21ClN6O2 and molecular weight 436.14 g/mol. IUPAC: 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid.
Chemical Property Profile of 洛沙坦羧酸
Property Insights of 洛沙坦羧酸
The XLogP value of 5.0 indicates that 洛沙坦羧酸 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 洛沙坦羧酸. Following Lipinski's Rule of Five, 洛沙坦羧酸 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛沙坦羧酸?
The CAS number of 洛沙坦羧酸 is 124750-92-1.
What is the molecular formula of 洛沙坦羧酸?
The molecular formula of 洛沙坦羧酸 is C22H21ClN6O2.
What is the molecular weight of 洛沙坦羧酸?
The molecular weight of 洛沙坦羧酸 is 436.14 g/mol.
Where can I buy 洛沙坦羧酸?
You can request a quote for 洛沙坦羧酸 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛沙坦羧酸?
Yes, KEHONG BIO provides custom synthesis services for 洛沙坦羧酸 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.