p-Hydroxy rosiglitazone
TL;DR: p-Hydroxy rosiglitazone (CAS 1246817-46-8) is a chemical compound with molecular formula C18H19N3O4S and molecular weight 373.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[4-[2-[(5-hydroxy-2-pyridinyl)-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: 5-Hydroxy Rosiglitazone, p-Hydroxy rosiglitazone, Para-hydroxy rosiglitazone, p-Hydroxyrosiglitazone, 5-Hydroxyrosiglitazone
| Molecular Formula | C18H19N3O4S |
|---|---|
| Molecular Weight | 373.11 g/mol |
| LogP | 2.1965 |
| Topological Polar Surface Area | 91.76 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 373.10962 |
| Heavy Atoms | 26 |
| Complexity | 780.02814 |
Chemical Identifiers
| CAS Number | 1246817-46-8 |
|---|---|
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=NC=C(C=C3)O |
Product Overview
p-Hydroxy rosiglitazone (CAS 1246817-46-8), with molecular formula C18H19N3O4S and molecular weight 373.11 g/mol. IUPAC: 5-[[4-[2-[(5-hydroxy-2-pyridinyl)-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of p-Hydroxy rosiglitazone
Property Insights of p-Hydroxy rosiglitazone
The XLogP value of 2.1965 suggests moderate lipophilicity, balancing water solubility and membrane permeability for p-Hydroxy rosiglitazone. The TPSA of 91.76 Ų falls within the moderate polarity range, balancing permeability and solubility for p-Hydroxy rosiglitazone. Following Lipinski's Rule of Five, p-Hydroxy rosiglitazone has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of p-Hydroxy rosiglitazone?
The CAS number of p-Hydroxy rosiglitazone is 1246817-46-8.
What is the molecular formula of p-Hydroxy rosiglitazone?
The molecular formula of p-Hydroxy rosiglitazone is C18H19N3O4S.
What is the molecular weight of p-Hydroxy rosiglitazone?
The molecular weight of p-Hydroxy rosiglitazone is 373.11 g/mol.
Where can I buy p-Hydroxy rosiglitazone?
You can request a quote for p-Hydroxy rosiglitazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for p-Hydroxy rosiglitazone?
Yes, KEHONG BIO provides custom synthesis services for p-Hydroxy rosiglitazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.