Donepezil Impurity 3
TL;DR: Donepezil Impurity 3 (CAS 1246814-90-3) is a chemical compound with molecular formula C24H27NO4 and molecular weight 393.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindene-1,3-dione
Also Known As: 3-Keto Donepezil, Donepezil Impurity 3, 3-Oxodonepezil, Donepezil 3-Oxo, Donepezil Impurity 15
| Molecular Formula | C24H27NO4 |
|---|---|
| Molecular Weight | 393.19 g/mol |
| LogP | 4.0013 |
| Topological Polar Surface Area | 55.84 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 393.194 |
| Heavy Atoms | 29 |
| Complexity | 857.59674 |
Chemical Identifiers
| CAS Number | 1246814-90-3 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=O)C(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC |
Product Overview
Donepezil Impurity 3 (CAS 1246814-90-3), with molecular formula C24H27NO4 and molecular weight 393.19 g/mol. IUPAC: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindene-1,3-dione.
Chemical Property Profile of Donepezil Impurity 3
Property Insights of Donepezil Impurity 3
The XLogP value of 4.0013 indicates that Donepezil Impurity 3 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.84 Ų, Donepezil Impurity 3 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Donepezil Impurity 3 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Donepezil Impurity 3?
The CAS number of Donepezil Impurity 3 is 1246814-90-3.
What is the molecular formula of Donepezil Impurity 3?
The molecular formula of Donepezil Impurity 3 is C24H27NO4.
What is the molecular weight of Donepezil Impurity 3?
The molecular weight of Donepezil Impurity 3 is 393.19 g/mol.
Where can I buy Donepezil Impurity 3?
You can request a quote for Donepezil Impurity 3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Donepezil Impurity 3?
Yes, KEHONG BIO provides custom synthesis services for Donepezil Impurity 3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.