Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate structure

Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate

TL;DR: Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate (CAS 123761-87-5) is a chemical compound with molecular formula C11H16Cl3NO5 and molecular weight 347.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

diethyl 2-(1-acetamido-2,2,2-trichloroethyl)propanedioate

Also Known As: Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate, diethyl 2-[1-(acetylamino)-2,2,2-trichloroethyl]malonate, AB01334947-02, diethyl 2-(1-acetamido-2,2,2-trichloroethyl)propanedioate, 1,3-diethyl 2-(2,2,2-trichloro-1-acetamidoethyl)propanedioate

CAS: 123761-87-5
Molecular Formula C11H16Cl3NO5
Molecular Weight 347.01 g/mol
LogP 1.6037
Topological Polar Surface Area 81.7 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 347.0094
Heavy Atoms 20
Complexity 351.56033

Chemical Identifiers

CAS Number 123761-87-5
SMILES CCOC(=O)C(C(C(Cl)(Cl)Cl)NC(=O)C)C(=O)OCC

Product Overview

Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate (CAS 123761-87-5), with molecular formula C11H16Cl3NO5 and molecular weight 347.01 g/mol. IUPAC: diethyl 2-(1-acetamido-2,2,2-trichloroethyl)propanedioate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate

XLogP
1.6037
TPSA (Topological Polar Surface Area)
81.7
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
20
Complexity
351.56033
Exact Mass
347.0094
Monoisotopic Mass
347.0094
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate

The XLogP value of 1.6037 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate. The TPSA of 81.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate. Following Lipinski's Rule of Five, Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate?

The CAS number of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate is 123761-87-5.

What is the molecular formula of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate?

The molecular formula of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate is C11H16Cl3NO5.

What is the molecular weight of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate?

The molecular weight of Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate is 347.01 g/mol.

Where can I buy Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate?

You can request a quote for Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate?

Yes, KEHONG BIO provides custom synthesis services for Diethyl 2-(1-acetamido-2,2,2-trichloroethyl)malonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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