Rosellichalasin structure

Rosellichalasin

TL;DR: Rosellichalasin (CAS 123452-64-2) is a chemical compound with molecular formula C28H33NO5 and molecular weight 463.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(5Z,10E)-18-benzyl-6,8,15,16-tetramethyl-2,14-dioxa-19-azatetracyclo[10.8.0.01,17.013,15]icosa-5,10-diene-3,7,20-trione

Also Known As: Rosellichalasin, (5Z,10E)-18-benzyl-6,8,15,16-tetramethyl-2,14-dioxa-19-azatetracyclo[10.8.0.01,17.013,15]icosa-5,10-diene-3,7,20-trione, (5Z,10E)-18-benzyl-6,8,15,16-tetramethyl-2,14-dioxa-19-azatetracyclo(10.8.0.01,17.013,15)icosa-5,10-diene-3,7,20-trione, 3H-Oxacyclododecino(2,3-d)oxireno(f)isoindole-5,9,11(4H,8H,12H)-trione, 13,13a,14,14a,15a,15b-hexahydro-4,6,14,14a-tetramethyl-13-(phenylmethyl)-, (4S-(1E,4R*,6E,10aR*,13R*,13aR*,14R*,14aS*,15aR*,15bR*))-, 3H-Oxacyclododecino(2,3-d)oxireno(f)isoindole-5,9,11(4H,8H,12H)-trione, 13,13a,14,14a,15a,15b-hexahydro-4,6,14,14a-tetramethyl-13-(phenylmethyl)-, (4S-(1E,4R*,6E,10aR*,13R*,13aR*,14R*,14aS*,15aR*,15bR*))-

CAS: 123452-64-2
Molecular Formula C28H33NO5
Molecular Weight 463.24 g/mol
LogP 3.5506
Topological Polar Surface Area 85.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 2
Exact Mass 463.23587
Heavy Atoms 34
Complexity 1077.5272

Chemical Identifiers

CAS Number 123452-64-2
SMILES CC1C/C=C/C2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)C/C=C(\C1=O)/C)C)C

Product Overview

Rosellichalasin (CAS 123452-64-2), with molecular formula C28H33NO5 and molecular weight 463.24 g/mol. IUPAC: (5Z,10E)-18-benzyl-6,8,15,16-tetramethyl-2,14-dioxa-19-azatetracyclo[10.8.0.01,17.013,15]icosa-5,10-diene-3,7,20-trione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Rosellichalasin

XLogP
3.5506
TPSA (Topological Polar Surface Area)
85.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
2
Heavy Atoms
34
Complexity
1077.5272
Exact Mass
463.23587
Monoisotopic Mass
463.23587
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Rosellichalasin

The XLogP value of 3.5506 indicates that Rosellichalasin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Rosellichalasin. Following Lipinski's Rule of Five, Rosellichalasin has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Rosellichalasin?

The CAS number of Rosellichalasin is 123452-64-2.

What is the molecular formula of Rosellichalasin?

The molecular formula of Rosellichalasin is C28H33NO5.

What is the molecular weight of Rosellichalasin?

The molecular weight of Rosellichalasin is 463.24 g/mol.

Where can I buy Rosellichalasin?

You can request a quote for Rosellichalasin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Rosellichalasin?

Yes, KEHONG BIO provides custom synthesis services for Rosellichalasin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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