N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide
TL;DR: N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide (CAS 1232007-12-3) is a chemical compound with molecular formula C16H11F3N2O2S and molecular weight 352.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamide
Also Known As: N-(8-Quinolyl)-4-(trifluoromethyl)benzenesulfonamide, N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide, J2.849.169G, N-Quinolin-8-yl-4-trifluoromethyl-benzenesulfonamide, N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamide
| Molecular Formula | C16H11F3N2O2S |
|---|---|
| Molecular Weight | 352.05 g/mol |
| LogP | 4.0544 |
| Topological Polar Surface Area | 59.06 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 352.04935 |
| Heavy Atoms | 24 |
| Complexity | 978.8752 |
Chemical Identifiers
| CAS Number | 1232007-12-3 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)C(F)(F)F)N=CC=C2 |
Product Overview
N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide (CAS 1232007-12-3), with molecular formula C16H11F3N2O2S and molecular weight 352.05 g/mol. IUPAC: N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamide.
Chemical Property Profile of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide
Property Insights of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide
The XLogP value of 4.0544 indicates that N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.06 Ų, N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide?
The CAS number of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide is 1232007-12-3.
What is the molecular formula of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide?
The molecular formula of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide is C16H11F3N2O2S.
What is the molecular weight of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide?
The molecular weight of N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide is 352.05 g/mol.
Where can I buy N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide?
You can request a quote for N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide?
Yes, KEHONG BIO provides custom synthesis services for N-(quinolin-8-yl)-4-(trifluoromethyl)benzene-1-sulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.