5-(difluoromethyl)-3-phenyl-1H-pyrazole
TL;DR: 5-(difluoromethyl)-3-phenyl-1H-pyrazole (CAS 122980-86-3) is a chemical compound with molecular formula C10H8F2N2 and molecular weight 194.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(difluoromethyl)-3-phenyl-1H-pyrazole
Also Known As: 3-Difluoromethyl-5-phenylpyrazole, 5-(difluoromethyl)-3-phenyl-1H-pyrazole, 3-(difluoromethyl)-5-phenyl-1H-pyrazole, 3(5)-Difluoromethyl-5(3)-phenylpyrazole, 1H-Pyrazole,3-(difluoromethyl)-5-phenyl-
| Molecular Formula | C10H8F2N2 |
|---|---|
| Molecular Weight | 194.07 g/mol |
| LogP | 3.0143 |
| Topological Polar Surface Area | 28.68 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 194.06555 |
| Heavy Atoms | 14 |
| Complexity | 409.07016 |
Chemical Identifiers
| CAS Number | 122980-86-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NNC(=C2)C(F)F |
Product Overview
5-(difluoromethyl)-3-phenyl-1H-pyrazole (CAS 122980-86-3), with molecular formula C10H8F2N2 and molecular weight 194.07 g/mol. IUPAC: 5-(difluoromethyl)-3-phenyl-1H-pyrazole.
Chemical Property Profile of 5-(difluoromethyl)-3-phenyl-1H-pyrazole
Property Insights of 5-(difluoromethyl)-3-phenyl-1H-pyrazole
The XLogP value of 3.0143 indicates that 5-(difluoromethyl)-3-phenyl-1H-pyrazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.68 Ų, 5-(difluoromethyl)-3-phenyl-1H-pyrazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(difluoromethyl)-3-phenyl-1H-pyrazole has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(difluoromethyl)-3-phenyl-1H-pyrazole?
The CAS number of 5-(difluoromethyl)-3-phenyl-1H-pyrazole is 122980-86-3.
What is the molecular formula of 5-(difluoromethyl)-3-phenyl-1H-pyrazole?
The molecular formula of 5-(difluoromethyl)-3-phenyl-1H-pyrazole is C10H8F2N2.
What is the molecular weight of 5-(difluoromethyl)-3-phenyl-1H-pyrazole?
The molecular weight of 5-(difluoromethyl)-3-phenyl-1H-pyrazole is 194.07 g/mol.
Where can I buy 5-(difluoromethyl)-3-phenyl-1H-pyrazole?
You can request a quote for 5-(difluoromethyl)-3-phenyl-1H-pyrazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(difluoromethyl)-3-phenyl-1H-pyrazole?
Yes, KEHONG BIO provides custom synthesis services for 5-(difluoromethyl)-3-phenyl-1H-pyrazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.