納美芬
TL;DR: 納美芬 (CAS 1228646-70-5) is a chemical compound with molecular formula C21H25NO3 and molecular weight 339.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
納美芬
(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Also Known As: nalmefene, Nalmetrene, Nalmefeno, Nalmefenum, Selincro
| Molecular Formula | C21H25NO3 |
|---|---|
| Molecular Weight | 339.18 g/mol |
| LogP | 2.5125 |
| Topological Polar Surface Area | 52.93 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 339.18344 |
| Heavy Atoms | 25 |
| Complexity | 800.57605 |
Chemical Identifiers
| CAS Number | 1228646-70-5 |
|---|---|
| SMILES | C=C1CC[C@]2([C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3CC6CC6)O |
Product Overview
納美芬 (CAS 1228646-70-5), with molecular formula C21H25NO3 and molecular weight 339.18 g/mol. IUPAC: (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol.
Chemical Property Profile of 納美芬
Property Insights of 納美芬
The XLogP value of 2.5125 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 納美芬. With a topological polar surface area (TPSA) of 52.93 Ų, 納美芬 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 納美芬 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 納美芬?
The CAS number of 納美芬 is 1228646-70-5.
What is the molecular formula of 納美芬?
The molecular formula of 納美芬 is C21H25NO3.
What is the molecular weight of 納美芬?
The molecular weight of 納美芬 is 339.18 g/mol.
Where can I buy 納美芬?
You can request a quote for 納美芬 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 納美芬?
Yes, KEHONG BIO provides custom synthesis services for 納美芬 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.