Englitazone
TL;DR: Englitazone (CAS 122228-35-7) is a chemical compound with molecular formula C20H19NO3S and molecular weight 353.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[(2R)-2-benzyl-3,4-dihydro-2H-chromen-6-yl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: englitazone, englitazona, englitazonum, Englitazone [INN], CP 68722
| Molecular Formula | C20H19NO3S |
|---|---|
| Molecular Weight | 353.11 g/mol |
| LogP | 3.517 |
| Topological Polar Surface Area | 55.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 353.10855 |
| Heavy Atoms | 25 |
| Complexity | 805.8435 |
Chemical Identifiers
| CAS Number | 122228-35-7 |
|---|---|
| SMILES | C1CC2=C(C=CC(=C2)CC3C(=O)NC(=O)S3)O[C@H]1CC4=CC=CC=C4 |
Product Overview
Englitazone (CAS 122228-35-7), with molecular formula C20H19NO3S and molecular weight 353.11 g/mol. IUPAC: 5-[[(2R)-2-benzyl-3,4-dihydro-2H-chromen-6-yl]methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of Englitazone
Property Insights of Englitazone
The XLogP value of 3.517 indicates that Englitazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Englitazone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Englitazone has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Englitazone?
The CAS number of Englitazone is 122228-35-7.
What is the molecular formula of Englitazone?
The molecular formula of Englitazone is C20H19NO3S.
What is the molecular weight of Englitazone?
The molecular weight of Englitazone is 353.11 g/mol.
Where can I buy Englitazone?
You can request a quote for Englitazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Englitazone?
Yes, KEHONG BIO provides custom synthesis services for Englitazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.