Fmoc-L-2,4,5-Trifluorophenylalanine
TL;DR: Fmoc-L-2,4,5-Trifluorophenylalanine (CAS 1217837-13-2) is a chemical compound with molecular formula C24H18F3NO4 and molecular weight 441.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2,4,5-trifluorophenyl)propanoic acid
Also Known As: Fmoc-L-2,4,5-Trifluorophenylalanine, Fmoc-L-2,4,5-Trifluorophe, Fmoc-2,4,5-Trifluoro-L-Phenylalanine, (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4,5-trifluorophenyl)propanoic acid, Fmoc-Phe(2,4,5-F3)-OH
| Molecular Formula | C24H18F3NO4 |
|---|---|
| Molecular Weight | 441.12 g/mol |
| LogP | 4.6383 |
| Topological Polar Surface Area | 75.63 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 441.1188 |
| Heavy Atoms | 32 |
| Complexity | 1152.1119 |
Chemical Identifiers
| CAS Number | 1217837-13-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CC(=C(C=C4F)F)F)C(=O)O |
Product Overview
Fmoc-L-2,4,5-Trifluorophenylalanine (CAS 1217837-13-2), with molecular formula C24H18F3NO4 and molecular weight 441.12 g/mol. IUPAC: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2,4,5-trifluorophenyl)propanoic acid.
Chemical Property Profile of Fmoc-L-2,4,5-Trifluorophenylalanine
Property Insights of Fmoc-L-2,4,5-Trifluorophenylalanine
The XLogP value of 4.6383 indicates that Fmoc-L-2,4,5-Trifluorophenylalanine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.63 Ų falls within the moderate polarity range, balancing permeability and solubility for Fmoc-L-2,4,5-Trifluorophenylalanine. Following Lipinski's Rule of Five, Fmoc-L-2,4,5-Trifluorophenylalanine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fmoc-L-2,4,5-Trifluorophenylalanine?
The CAS number of Fmoc-L-2,4,5-Trifluorophenylalanine is 1217837-13-2.
What is the molecular formula of Fmoc-L-2,4,5-Trifluorophenylalanine?
The molecular formula of Fmoc-L-2,4,5-Trifluorophenylalanine is C24H18F3NO4.
What is the molecular weight of Fmoc-L-2,4,5-Trifluorophenylalanine?
The molecular weight of Fmoc-L-2,4,5-Trifluorophenylalanine is 441.12 g/mol.
Where can I buy Fmoc-L-2,4,5-Trifluorophenylalanine?
You can request a quote for Fmoc-L-2,4,5-Trifluorophenylalanine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fmoc-L-2,4,5-Trifluorophenylalanine?
Yes, KEHONG BIO provides custom synthesis services for Fmoc-L-2,4,5-Trifluorophenylalanine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.