匹伐他汀
TL;DR: 匹伐他汀 (CAS 121659-03-8) is a chemical compound with molecular formula C25H24FNO4 and molecular weight 421.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
匹伐他汀
(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
Also Known As: Pitavastatin, Itavastatin, Livalo, pitavastatine, pitavastatinum
| Molecular Formula | C25H24FNO4 |
|---|---|
| Molecular Weight | 421.17 g/mol |
| LogP | 4.5181 |
| Topological Polar Surface Area | 90.65 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 421.16895 |
| Heavy Atoms | 31 |
| Complexity | 1122.3202 |
Chemical Identifiers
| CAS Number | 121659-03-8 |
|---|---|
| SMILES | C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@H](C[C@H](CC(=O)O)O)O)C4=CC=C(C=C4)F |
Product Overview
匹伐他汀 (CAS 121659-03-8), with molecular formula C25H24FNO4 and molecular weight 421.17 g/mol. IUPAC: (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid.
Chemical Property Profile of 匹伐他汀
Property Insights of 匹伐他汀
The XLogP value of 4.5181 indicates that 匹伐他汀 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.65 Ų falls within the moderate polarity range, balancing permeability and solubility for 匹伐他汀. Following Lipinski's Rule of Five, 匹伐他汀 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 匹伐他汀?
The CAS number of 匹伐他汀 is 121659-03-8.
What is the molecular formula of 匹伐他汀?
The molecular formula of 匹伐他汀 is C25H24FNO4.
What is the molecular weight of 匹伐他汀?
The molecular weight of 匹伐他汀 is 421.17 g/mol.
Where can I buy 匹伐他汀?
You can request a quote for 匹伐他汀 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 匹伐他汀?
Yes, KEHONG BIO provides custom synthesis services for 匹伐他汀 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.