5-(N,N-二甲基)阿米洛利
TL;DR: 5-(N,N-二甲基)阿米洛利 (CAS 1214-79-5) is a chemical compound with molecular formula C8H12ClN7O and molecular weight 257.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(N,N-二甲基)阿米洛利
3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide
Also Known As: 5-dimethylamiloride, dimethylamiloride, Dimethyl amiloride, dimethyl amylioride, Dma cpd
| Molecular Formula | C8H12ClN7O |
|---|---|
| Molecular Weight | 257.08 g/mol |
| LogP | 0.1 |
| Topological Polar Surface Area | 137.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 257.0792 |
| Heavy Atoms | 17 |
| Complexity | 317.0 |
Chemical Identifiers
| CAS Number | 1214-79-5 |
|---|---|
| SMILES | CN(C)C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N |
| InChIKey | RXMUPNVSYKGKMY-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-(N,N-二甲基)阿米洛利 (CAS 1214-79-5), with molecular formula C8H12ClN7O and molecular weight 257.08 g/mol. IUPAC: 3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide.
Chemical Property Profile of 5-(N,N-二甲基)阿米洛利
Property Insights of 5-(N,N-二甲基)阿米洛利
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(N,N-二甲基)阿米洛利. The TPSA of 137.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(N,N-二甲基)阿米洛利. Following Lipinski's Rule of Five, 5-(N,N-二甲基)阿米洛利 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(N,N-二甲基)阿米洛利?
The CAS number of 5-(N,N-二甲基)阿米洛利 is 1214-79-5.
What is the molecular formula of 5-(N,N-二甲基)阿米洛利?
The molecular formula of 5-(N,N-二甲基)阿米洛利 is C8H12ClN7O.
What is the molecular weight of 5-(N,N-二甲基)阿米洛利?
The molecular weight of 5-(N,N-二甲基)阿米洛利 is 257.08 g/mol.
Where can I buy 5-(N,N-二甲基)阿米洛利?
You can request a quote for 5-(N,N-二甲基)阿米洛利 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(N,N-二甲基)阿米洛利?
Yes, KEHONG BIO provides custom synthesis services for 5-(N,N-二甲基)阿米洛利 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.