Donepezil Hydrochloride
TL;DR: Donepezil Hydrochloride (CAS 120011-70-3) is a chemical compound with molecular formula C24H30ClNO3 and molecular weight 415.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
Also Known As: Donepezil hydrochloride, Donepezil HCl, Aricept, donepezil, BNAG
| Molecular Formula | C24H30ClNO3 |
|---|---|
| Molecular Weight | 415.19 g/mol |
| LogP | 4.78 |
| Topological Polar Surface Area | 38.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 415.1914 |
| Heavy Atoms | 29 |
| Complexity | 510.0 |
Chemical Identifiers
| CAS Number | 120011-70-3 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl |
| InChIKey | XWAIAVWHZJNZQQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Donepezil Hydrochloride (CAS 120011-70-3), with molecular formula C24H30ClNO3 and molecular weight 415.19 g/mol. IUPAC: 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride.
Chemical Property Profile of Donepezil Hydrochloride
Property Insights of Donepezil Hydrochloride
The XLogP value of 4.78 indicates that Donepezil Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.8 Ų, Donepezil Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Donepezil Hydrochloride has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Donepezil Hydrochloride?
The CAS number of Donepezil Hydrochloride is 120011-70-3.
What is the molecular formula of Donepezil Hydrochloride?
The molecular formula of Donepezil Hydrochloride is C24H30ClNO3.
What is the molecular weight of Donepezil Hydrochloride?
The molecular weight of Donepezil Hydrochloride is 415.19 g/mol.
Where can I buy Donepezil Hydrochloride?
You can request a quote for Donepezil Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Donepezil Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Donepezil Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.