氯雷他定酮
TL;DR: 氯雷他定酮 (CAS 119770-60-4) is a chemical compound with molecular formula C20H23ClN2O and molecular weight 342.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氯雷他定酮
[3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl]-(1-methylpiperidin-4-yl)methanone
Also Known As: Loratadine ketone, Loratadine Impurity 27, Desloratadine Impurity 20, Desloratadine Ketone Impurity, 2,4-Dichloroquinolin-3-carboxaldehyde
| Molecular Formula | C20H23ClN2O |
|---|---|
| Molecular Weight | 342.15 g/mol |
| LogP | 4.0447 |
| Topological Polar Surface Area | 33.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 342.1499 |
| Heavy Atoms | 24 |
| Complexity | 708.29 |
Chemical Identifiers
| CAS Number | 119770-60-4 |
|---|---|
| SMILES | CN1CCC(CC1)C(=O)C2=C(C=CC=N2)CCC3=CC(=CC=C3)Cl |
Product Overview
氯雷他定酮 (CAS 119770-60-4), with molecular formula C20H23ClN2O and molecular weight 342.15 g/mol. IUPAC: [3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl]-(1-methylpiperidin-4-yl)methanone.
Chemical Property Profile of 氯雷他定酮
Property Insights of 氯雷他定酮
The XLogP value of 4.0447 indicates that 氯雷他定酮 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 33.2 Ų, 氯雷他定酮 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 氯雷他定酮 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氯雷他定酮?
The CAS number of 氯雷他定酮 is 119770-60-4.
What is the molecular formula of 氯雷他定酮?
The molecular formula of 氯雷他定酮 is C20H23ClN2O.
What is the molecular weight of 氯雷他定酮?
The molecular weight of 氯雷他定酮 is 342.15 g/mol.
Where can I buy 氯雷他定酮?
You can request a quote for 氯雷他定酮 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氯雷他定酮?
Yes, KEHONG BIO provides custom synthesis services for 氯雷他定酮 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.