5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
概要：5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one（CAS 1189453-50-6）是一种化学化合物，分子式为C23H25N3O4S，分子量为439.16 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-1-(3,5-dimethylphenyl)-6-hydroxy-2-sulfanylidenepyrimidin-4-one
又称：5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, 5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-1-(3,5-dimethylphenyl)-6-hydroxy-2-sulfanylidenepyrimidin-4-one
| 分子式 | C23H25N3O4S |
|---|---|
| 分子量 | 439.16 g/mol |
| LogP | 3.46983 |
| 拓扑极性表面积 | 88.51 Ų |
| 氢键供体数 | 3 |
| 氢键受体数 | 6 |
| 可旋转键数 | 4 |
| 精确质量 | 439.1566 |
| 重原子数 | 31 |
| 复杂度 | 1258.7839 |
化学标识符
| CAS 编号 | 1189453-50-6 |
|---|---|
| SMILES | CC1=CC(=CC(=C1)N2C(=C(C(=O)NC2=S)C3C4=CC(=C(C=C4CCN3)OC)OC)O)C |
产品概述
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one（CAS 1189453-50-6），分子式为C23H25N3O4S，分子量为439.16 g/mol。IUPAC名：5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-1-(3,5-dimethylphenyl)-6-hydroxy-2-sulfanylidenepyrimidin-4-one。
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one化学性质概览
属性洞察：5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的XLogP值为3.46983，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为88.51 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one有3个氢键供体和6个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的CAS号是多少？
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的CAS号为1189453-50-6。
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的分子式是什么？
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的分子式为C23H25N3O4S。
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的分子量是多少？
5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的分子量为439.16 g/mol。
在哪里可以购买5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one？
您可以直接向科弘生物询价5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one的定制合成服务？
是的，科弘生物提供5-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-3-(3,5-dimethylphenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。