Licofelone
TL;DR: Licofelone (CAS 1189427-04-0) is a chemical compound with molecular formula C23H22ClNO2 and molecular weight 379.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid
Also Known As: Licofelone, licofelona, Licofelone [INN], licofelonum, null
| Molecular Formula | C23H22ClNO2 |
|---|---|
| Molecular Weight | 379.13 g/mol |
| LogP | 5.2 |
| Topological Polar Surface Area | 42.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 379.1339 |
| Heavy Atoms | 27 |
| Complexity | 536.0 |
Chemical Identifiers
| CAS Number | 1189427-04-0 |
|---|---|
| SMILES | CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C |
| InChIKey | UAWXGRJVZSAUSZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Licofelone (CAS 1189427-04-0), with molecular formula C23H22ClNO2 and molecular weight 379.13 g/mol. IUPAC: 2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid.
Chemical Property Profile of Licofelone
Property Insights of Licofelone
The XLogP value of 5.2 indicates that Licofelone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.2 Ų, Licofelone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Licofelone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Licofelone?
The CAS number of Licofelone is 1189427-04-0.
What is the molecular formula of Licofelone?
The molecular formula of Licofelone is C23H22ClNO2.
What is the molecular weight of Licofelone?
The molecular weight of Licofelone is 379.13 g/mol.
Where can I buy Licofelone?
You can request a quote for Licofelone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Licofelone?
Yes, KEHONG BIO provides custom synthesis services for Licofelone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.