2,2,10,10-Tetrafluoro-13-dehydroprostacyclin
TL;DR: 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin (CAS 118916-24-8) is a chemical compound with molecular formula C20H28F4O5 and molecular weight 424.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(4R,5S,6aS)-6,6-difluoro-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3a,4,5,6a-tetrahydro-3H-cyclopenta[b]furan-2-ylidene]-2,2-difluoropentanoic acid
Also Known As: 4F-Pgi2, 2,2,10,10-Tetrafluoro-13-dehydro-pgi2, (R)-2-(4-Bromophenyl)-pyrrolidine, 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin, (5Z)-5-[(4R,5S,6aS)-6,6-difluoro-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3a,4,5,6a-tetrahydro-3H-cyclopenta[b]furan-2-ylidene]-2,2-difluoropentanoic acid
| Molecular Formula | C20H28F4O5 |
|---|---|
| Molecular Weight | 424.19 g/mol |
| LogP | 3.8989 |
| Topological Polar Surface Area | 86.99 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 10 |
| Exact Mass | 424.1873 |
| Heavy Atoms | 29 |
| Complexity | 634.3611 |
Chemical Identifiers
| CAS Number | 118916-24-8 |
|---|---|
| SMILES | CCCCC[C@@H](/C=C/[C@H]1[C@@H](C([C@@H]2C1C/C(=C/CCC(C(=O)O)(F)F)/O2)(F)F)O)O |
Product Overview
2,2,10,10-Tetrafluoro-13-dehydroprostacyclin (CAS 118916-24-8), with molecular formula C20H28F4O5 and molecular weight 424.19 g/mol. IUPAC: (5Z)-5-[(4R,5S,6aS)-6,6-difluoro-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3a,4,5,6a-tetrahydro-3H-cyclopenta[b]furan-2-ylidene]-2,2-difluoropentanoic acid.
Chemical Property Profile of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin
Property Insights of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin
The XLogP value of 3.8989 indicates that 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.99 Ų falls within the moderate polarity range, balancing permeability and solubility for 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin. Following Lipinski's Rule of Five, 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin?
The CAS number of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin is 118916-24-8.
What is the molecular formula of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin?
The molecular formula of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin is C20H28F4O5.
What is the molecular weight of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin?
The molecular weight of 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin is 424.19 g/mol.
Where can I buy 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin?
You can request a quote for 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin?
Yes, KEHONG BIO provides custom synthesis services for 2,2,10,10-Tetrafluoro-13-dehydroprostacyclin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.