Isavuconazole Impurity 24
TL;DR: Isavuconazole Impurity 24 (CAS 1176988-44-5) is a chemical compound with molecular formula C22H17F2N5OS and molecular weight 437.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[2-[(2S,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
Also Known As: Isavuconazole, Isavuconazole Impurity 24, IsavuconazoleImpurity22, Isavuconazole Impurity 38, ISAVUCONAZOLE IMPURITY E
| Molecular Formula | C22H17F2N5OS |
|---|---|
| Molecular Weight | 437.11 g/mol |
| LogP | 4.24298 |
| Topological Polar Surface Area | 87.62 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 437.11218 |
| Heavy Atoms | 31 |
| Complexity | 1233.7822 |
Chemical Identifiers
| CAS Number | 1176988-44-5 |
|---|---|
| SMILES | C[C@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=NC=N3)(C4=C(C=CC(=C4)F)F)O |
Product Overview
Isavuconazole Impurity 24 (CAS 1176988-44-5), with molecular formula C22H17F2N5OS and molecular weight 437.11 g/mol. IUPAC: 4-[2-[(2S,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile.
Chemical Property Profile of Isavuconazole Impurity 24
Property Insights of Isavuconazole Impurity 24
The XLogP value of 4.24298 indicates that Isavuconazole Impurity 24 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 87.62 Ų falls within the moderate polarity range, balancing permeability and solubility for Isavuconazole Impurity 24. Following Lipinski's Rule of Five, Isavuconazole Impurity 24 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Isavuconazole Impurity 24?
The CAS number of Isavuconazole Impurity 24 is 1176988-44-5.
What is the molecular formula of Isavuconazole Impurity 24?
The molecular formula of Isavuconazole Impurity 24 is C22H17F2N5OS.
What is the molecular weight of Isavuconazole Impurity 24?
The molecular weight of Isavuconazole Impurity 24 is 437.11 g/mol.
Where can I buy Isavuconazole Impurity 24?
You can request a quote for Isavuconazole Impurity 24 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Isavuconazole Impurity 24?
Yes, KEHONG BIO provides custom synthesis services for Isavuconazole Impurity 24 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.