RefChem:1071753 structure

RefChem:1071753

TL;DR: RefChem:1071753 (CAS 117267-50-2) is a chemical compound with molecular formula C20H15ClN6 and molecular weight 374.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

8-chloro-1-(5-methyl-1H-imidazol-4-yl)-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Also Known As: 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-1-(5-methyl-1H-imidazol-4-yl)-6-phenyl-, 8-Chloro-1-(5-methyl-4-imidazolyl)-6-phenyl-4H-s-triazolo(4,3-a)-1,4-benzodiazepine, AE-641/30155041, 8-Chloro-1-(5-methyl-1H-imidazol-4-yl)-6-phenyl-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine, (1E)-8-chloro-1-(5-methylimidazol-4-ylidene)-6-phenyl-2,4-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

CAS: 117267-50-2
Molecular Formula C20H15ClN6
Molecular Weight 374.10 g/mol
LogP 3.97022
Topological Polar Surface Area 71.75 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 374.10468
Heavy Atoms 27
Complexity 1172.4175

Chemical Identifiers

CAS Number 117267-50-2
SMILES CC1=C(N=CN1)C2=NN=C3N2C4=C(C=C(C=C4)Cl)C(=NC3)C5=CC=CC=C5

Product Overview

RefChem:1071753 (CAS 117267-50-2), with molecular formula C20H15ClN6 and molecular weight 374.10 g/mol. IUPAC: 8-chloro-1-(5-methyl-1H-imidazol-4-yl)-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:1071753

XLogP
3.97022
TPSA (Topological Polar Surface Area)
71.75
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
27
Complexity
1172.4175
Exact Mass
374.10468
Monoisotopic Mass
374.10468
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:1071753

The XLogP value of 3.97022 indicates that RefChem:1071753 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.75 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:1071753. Following Lipinski's Rule of Five, RefChem:1071753 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:1071753?

The CAS number of RefChem:1071753 is 117267-50-2.

What is the molecular formula of RefChem:1071753?

The molecular formula of RefChem:1071753 is C20H15ClN6.

What is the molecular weight of RefChem:1071753?

The molecular weight of RefChem:1071753 is 374.10 g/mol.

Where can I buy RefChem:1071753?

You can request a quote for RefChem:1071753 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:1071753?

Yes, KEHONG BIO provides custom synthesis services for RefChem:1071753 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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