Semotiadil fumarate structure

Semotiadil fumarate

TL;DR: Semotiadil fumarate (CAS 116476-14-3) is a chemical compound with molecular formula C33H36N2O10S and molecular weight 652.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2R)-2-[2-[3-[2-(1,3-benzodioxol-5-yloxy)ethyl-methylamino]propoxy]-5-methoxyphenyl]-4-methyl-1,4-benzothiazin-3-one;(E)-but-2-enedioic acid

Also Known As: Semotiadil fumarate, Sesamodil fumarate, Sesamodil, Semotiadil, SEMOTIADIL FUMARATE [MI]

CAS: 116476-14-3
Molecular Formula C33H36N2O10S
Molecular Weight 652.21 g/mol
LogP 4.7252
Topological Polar Surface Area 144.3 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 10
Rotatable Bonds 13
Exact Mass 652.20905
Heavy Atoms 46
Complexity 1547.1376

Chemical Identifiers

CAS Number 116476-14-3
SMILES CN1C2=CC=CC=C2S[C@@H](C1=O)C3=C(C=CC(=C3)OC)OCCCN(C)CCOC4=CC5=C(C=C4)OCO5.C(=C/C(=O)O)\C(=O)O

Product Overview

Semotiadil fumarate (CAS 116476-14-3), with molecular formula C33H36N2O10S and molecular weight 652.21 g/mol. IUPAC: (2R)-2-[2-[3-[2-(1,3-benzodioxol-5-yloxy)ethyl-methylamino]propoxy]-5-methoxyphenyl]-4-methyl-1,4-benzothiazin-3-one;(E)-but-2-enedioic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Semotiadil fumarate

XLogP
4.7252
TPSA (Topological Polar Surface Area)
144.3
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
10
Rotatable Bonds
13
Heavy Atoms
46
Complexity
1547.1376
Exact Mass
652.20905
Monoisotopic Mass
652.20905
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Semotiadil fumarate

The XLogP value of 4.7252 indicates that Semotiadil fumarate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 144.3 Ų indicates high polarity, suggesting Semotiadil fumarate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Semotiadil fumarate has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Semotiadil fumarate?

The CAS number of Semotiadil fumarate is 116476-14-3.

What is the molecular formula of Semotiadil fumarate?

The molecular formula of Semotiadil fumarate is C33H36N2O10S.

What is the molecular weight of Semotiadil fumarate?

The molecular weight of Semotiadil fumarate is 652.21 g/mol.

Where can I buy Semotiadil fumarate?

You can request a quote for Semotiadil fumarate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Semotiadil fumarate?

Yes, KEHONG BIO provides custom synthesis services for Semotiadil fumarate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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