![(E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone structure](/static/products/116/1164557-26-9.png)
(E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone
TL;DR: (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone (CAS 1164557-26-9) is a chemical compound with molecular formula C24H27N3O2 and molecular weight 389.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(4-methoxyphenyl)-3-[1-[(4-methylpiperazin-1-yl)methyl]indol-3-yl]prop-2-en-1-one
Also Known As: (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone, (E)-1-(4-methoxyphenyl)-3-[1-[(4-methylpiperazin-1-yl)methyl]indol-3-yl]prop-2-en-1-one, (E)-1-(4-methoxyphenyl)-3-[1-[(4-methyl-1-piperazinyl)methyl]-3-indolyl]-2-propen-1-one, (E)-1-(4-methoxyphenyl)-3-[1-[(4-methylpiperazino)methyl]indol-3-yl]prop-2-en-1-one, (2E)-1-(4-methoxyphenyl)-3-{1-[(4-methylpiperazin-1-yl)methyl]-1H-indol-3-yl}prop-2-en-1-one
| Molecular Formula | C24H27N3O2 |
|---|---|
| Molecular Weight | 389.21 g/mol |
| LogP | 3.7509 |
| Topological Polar Surface Area | 37.71 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 389.21033 |
| Heavy Atoms | 29 |
| Complexity | 1012.28674 |
Chemical Identifiers
| CAS Number | 1164557-26-9 |
|---|---|
| SMILES | CN1CCN(CC1)CN2C=C(C3=CC=CC=C32)/C=C/C(=O)C4=CC=C(C=C4)OC |
Product Overview
(E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone (CAS 1164557-26-9), with molecular formula C24H27N3O2 and molecular weight 389.21 g/mol. IUPAC: (E)-1-(4-methoxyphenyl)-3-[1-[(4-methylpiperazin-1-yl)methyl]indol-3-yl]prop-2-en-1-one.
Chemical Property Profile of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone
Property Insights of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone
The XLogP value of 3.7509 indicates that (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.71 Ų, (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone?
The CAS number of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone is 1164557-26-9.
What is the molecular formula of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone?
The molecular formula of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone is C24H27N3O2.
What is the molecular weight of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone?
The molecular weight of (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone is 389.21 g/mol.
Where can I buy (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone?
You can request a quote for (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone?
Yes, KEHONG BIO provides custom synthesis services for (E)-1-(4-Methoxy-phenyl)-3-[1-(4-methyl-piperazin-1-ylmethyl)-1H-indol-3-yl]-propenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.