(E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate structure

(E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate

TL;DR: (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate (CAS 1164543-02-5) is a chemical compound with molecular formula C22H23ClN2O3 and molecular weight 398.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl (2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-oxopropanoate

Also Known As: (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate, ethyl (2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-oxopropanoate, ethyl (2E)-3-[(2-chlorophenyl)amino]-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate, ETHYL 2-[(2-CHLOROPHENYL)CARBAMOYL]-2-[(1E)-3,3-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YLIDENE]ACETATE, ethyl 3-[(2-chlorophenyl)amino]-2-(3,3-dimethyl-3,4-dihydro-1(2H)-isoquinolinylidene)-3-oxopropanoate

CAS: 1164543-02-5
Molecular Formula C22H23ClN2O3
Molecular Weight 398.14 g/mol
LogP 4.1772
Topological Polar Surface Area 67.43 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 398.1397
Heavy Atoms 28
Complexity 950.303

Chemical Identifiers

CAS Number 1164543-02-5
SMILES CCOC(=O)/C(=C/1\C2=CC=CC=C2CC(N1)(C)C)/C(=O)NC3=CC=CC=C3Cl

Product Overview

(E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate (CAS 1164543-02-5), with molecular formula C22H23ClN2O3 and molecular weight 398.14 g/mol. IUPAC: ethyl (2E)-3-(2-chloroanilino)-2-(3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)-3-oxopropanoate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate

XLogP
4.1772
TPSA (Topological Polar Surface Area)
67.43
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
28
Complexity
950.303
Exact Mass
398.1397
Monoisotopic Mass
398.1397
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate

The XLogP value of 4.1772 indicates that (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.43 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate. Following Lipinski's Rule of Five, (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate?

The CAS number of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate is 1164543-02-5.

What is the molecular formula of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate?

The molecular formula of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate is C22H23ClN2O3.

What is the molecular weight of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate?

The molecular weight of (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate is 398.14 g/mol.

Where can I buy (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate?

You can request a quote for (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate?

Yes, KEHONG BIO provides custom synthesis services for (E)-ethyl 3-((2-chlorophenyl)amino)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)-3-oxopropanoate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?