![(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide structure](/static/products/1164/1164532-42-6.webp)
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide
概要：(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide（CAS 1164532-42-6）是一种化学化合物，分子式为C25H25N5OS，分子量为443.18 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(E)-N-(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
又称：(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide, (E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-thiazolo[4,5-c]pyridin-2-yl]-2-propenamide, (E)-N-(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide, (E)-N-(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide, (E)-N-(5-benzyl-6,7-dihydro-4H-thiazolo[4,5-c]pyridin-2-yl)-2-cyano-3-[4-(dimethylamino)phenyl]acrylamide
| 分子式 | C25H25N5OS |
|---|---|
| 分子量 | 443.18 g/mol |
| LogP | 4.31308 |
| 拓扑极性表面积 | 72.26 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 6 |
| 可旋转键数 | 6 |
| 精确质量 | 443.17798 |
| 重原子数 | 32 |
| 复杂度 | 1159.293 |
化学标识符
| CAS 编号 | 1164532-42-6 |
|---|---|
| SMILES | CN(C)C1=CC=C(C=C1)/C=C(\C#N)/C(=O)NC2=NC3=C(S2)CCN(C3)CC4=CC=CC=C4 |
产品概述
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide（CAS 1164532-42-6），分子式为C25H25N5OS，分子量为443.18 g/mol。IUPAC名：(E)-N-(5-benzyl-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide。
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide化学性质概览
属性洞察：(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的XLogP值为4.31308，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为72.26 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide有1个氢键供体和6个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的CAS号是多少？
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的CAS号为1164532-42-6。
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的分子式是什么？
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的分子式为C25H25N5OS。
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的分子量是多少？
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的分子量为443.18 g/mol。
在哪里可以购买(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide？
您可以直接向科弘生物询价(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide的定制合成服务？
是的，科弘生物提供(E)-2-cyano-3-[4-(dimethylamino)phenyl]-N-[5-(phenylmethyl)-6,7-dihydro-4H-[1,3]thiazolo[4,5-c]pyridin-2-yl]prop-2-enamide及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。