(E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile
TL;DR: (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile (CAS 1164477-44-4) is a chemical compound with molecular formula C16H9FN2OS and molecular weight 296.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-fluorophenyl)-2-[4-(furan-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile
Also Known As: (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile, (E)-3-(4-fluorophenyl)-2-(4-(furan-2-yl)thiazol-2-yl)acrylonitrile, (2E)-3-(4-fluorophenyl)-2-[4-(furan-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile, (E)-3-(4-fluorophenyl)-2-[4-(furan-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile
| Molecular Formula | C16H9FN2OS |
|---|---|
| Molecular Weight | 296.04 g/mol |
| LogP | 4.60638 |
| Topological Polar Surface Area | 49.82 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 296.04196 |
| Heavy Atoms | 21 |
| Complexity | 810.8415 |
Chemical Identifiers
| CAS Number | 1164477-44-4 |
|---|---|
| SMILES | C1=COC(=C1)C2=CSC(=N2)/C(=C/C3=CC=C(C=C3)F)/C#N |
Product Overview
(E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile (CAS 1164477-44-4), with molecular formula C16H9FN2OS and molecular weight 296.04 g/mol. IUPAC: (E)-3-(4-fluorophenyl)-2-[4-(furan-2-yl)-1,3-thiazol-2-yl]prop-2-enenitrile.
Chemical Property Profile of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile
Property Insights of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile
The XLogP value of 4.60638 indicates that (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.82 Ų, (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile?
The CAS number of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile is 1164477-44-4.
What is the molecular formula of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile?
The molecular formula of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile is C16H9FN2OS.
What is the molecular weight of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile?
The molecular weight of (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile is 296.04 g/mol.
Where can I buy (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile?
You can request a quote for (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(4-Fluoro-phenyl)-2-(4-furan-2-yl-thiazol-2-yl)-acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.