![N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide structure](/static/products/1164/1164460-60-9.webp)
N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
TL;DR: N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide (CAS 1164460-60-9) is a chemical compound with molecular formula C19H13ClFN3O4S and molecular weight 433.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-chlorophenyl)-2-[(5Z)-5-[2-(4-fluoroanilino)-2-oxoethylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
Also Known As: N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide, N-(4-chlorophenyl)-2-[(5Z)-5-[2-(4-fluoroanilino)-2-oxoethylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide, (2Z)-2-(3-{2-[(4-chlorophenyl)amino]-2-oxoethyl}-2,4-dioxo-1,3-thiazolidin-5-ylidene)-N-(4-fluorophenyl)ethanamide, (Z)-N-(4-chlorophenyl)-2-(5-(2-((4-fluorophenyl)amino)-2-oxoethylidene)-2,4-dioxothiazolidin-3-yl)acetamide, N-p-fluorophenyl(Z)-{3-[(N-p-chlorophenylcarbamoyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene}acetamide
| Molecular Formula | C19H13ClFN3O4S |
|---|---|
| Molecular Weight | 433.03 g/mol |
| LogP | 3.6356 |
| Topological Polar Surface Area | 95.58 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 433.02994 |
| Heavy Atoms | 29 |
| Complexity | 1009.11926 |
Chemical Identifiers
| CAS Number | 1164460-60-9 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=O)/C=C\2/C(=O)N(C(=O)S2)CC(=O)NC3=CC=C(C=C3)Cl)F |
Product Overview
N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide (CAS 1164460-60-9), with molecular formula C19H13ClFN3O4S and molecular weight 433.03 g/mol. IUPAC: N-(4-chlorophenyl)-2-[(5Z)-5-[2-(4-fluoroanilino)-2-oxoethylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide.
Chemical Property Profile of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
Property Insights of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
The XLogP value of 3.6356 indicates that N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.58 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide. Following Lipinski's Rule of Five, N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide?
The CAS number of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide is 1164460-60-9.
What is the molecular formula of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide?
The molecular formula of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide is C19H13ClFN3O4S.
What is the molecular weight of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide?
The molecular weight of N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide is 433.03 g/mol.
Where can I buy N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide?
You can request a quote for N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-chlorophenyl)-2-[(5Z)-5-{[(4-fluorophenyl)carbamoyl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.