Ruzadolane structure

Ruzadolane

TL;DR: Ruzadolane (CAS 115762-17-9) is a chemical compound with molecular formula C18H19F2N5S and molecular weight 375.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]ethylsulfanyl]-[1,2,4]triazolo[4,3-a]pyridine

Also Known As: Ruzadolane, ruzadolano, ruzadolanum, Ruzadolane [INN], 2-Chloro-N-(2-chlorophenyl)acetamide

CAS: 115762-17-9
Molecular Formula C18H19F2N5S
Molecular Weight 375.13 g/mol
LogP 3.9
Topological Polar Surface Area 62.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 375.13293
Heavy Atoms 26
Complexity 451.0

Chemical Identifiers

CAS Number 115762-17-9
SMILES C1CN(CCN1CCSC2=NN=C3N2C=CC=C3)C4=C(C=C(C=C4)F)F
InChIKey LOKBLLCVOKCEFR-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (25 patents)

Product Overview

Ruzadolane (CAS 115762-17-9), with molecular formula C18H19F2N5S and molecular weight 375.13 g/mol. IUPAC: 3-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]ethylsulfanyl]-[1,2,4]triazolo[4,3-a]pyridine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ruzadolane

XLogP
3.9
TPSA (Topological Polar Surface Area)
62.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
26
Complexity
451.0
Exact Mass
375.13293
Monoisotopic Mass
375.13293
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ruzadolane

The XLogP value of 3.9 indicates that Ruzadolane is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Ruzadolane. Following Lipinski's Rule of Five, Ruzadolane has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ruzadolane?

The CAS number of Ruzadolane is 115762-17-9.

What is the molecular formula of Ruzadolane?

The molecular formula of Ruzadolane is C18H19F2N5S.

What is the molecular weight of Ruzadolane?

The molecular weight of Ruzadolane is 375.13 g/mol.

Where can I buy Ruzadolane?

You can request a quote for Ruzadolane directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ruzadolane?

Yes, KEHONG BIO provides custom synthesis services for Ruzadolane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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