thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate structure

thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate

TL;DR: thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate (CAS 115365-14-5) is a chemical compound with molecular formula C14H21N2O9P and molecular weight 392.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl [[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-methoxyphosphoryl]formate

Also Known As: thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate, thymidine 5'-[(ethoxycarbonyl)-O-methyl]phosphonate, Thymidine, 5'-[methyl(ethoxycarbonyl)phosphonate] (9CI), ((1-(2,4-Dioxo-5-methyl-1,2,3,4-tetrahyropyrimidin-1-yl)-2-deoxy-beta-D-erythro-pentofuranos-5-yl)oxy)methoxyphosphinecarboxylic acid ethyl ester oxide, ethyl [[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-methoxy-phosphoryl]formate

CAS: 115365-14-5
Molecular Formula C14H21N2O9P
Molecular Weight 392.10 g/mol
LogP 0.50602
Topological Polar Surface Area 146.15 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 9
Rotatable Bonds 7
Exact Mass 392.09848
Heavy Atoms 26
Complexity 817.37085

Chemical Identifiers

CAS Number 115365-14-5
SMILES CCOC(=O)P(=O)(OC)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)O

Product Overview

thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate (CAS 115365-14-5), with molecular formula C14H21N2O9P and molecular weight 392.10 g/mol. IUPAC: ethyl [[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-methoxyphosphoryl]formate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate

XLogP
0.50602
TPSA (Topological Polar Surface Area)
146.15
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
9
Rotatable Bonds
7
Heavy Atoms
26
Complexity
817.37085
Exact Mass
392.09848
Monoisotopic Mass
392.09848
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate

The XLogP value of 0.50602 suggests moderate lipophilicity, balancing water solubility and membrane permeability for thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate. The TPSA of 146.15 Ų indicates high polarity, suggesting thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate?

The CAS number of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate is 115365-14-5.

What is the molecular formula of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate?

The molecular formula of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate is C14H21N2O9P.

What is the molecular weight of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate?

The molecular weight of thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate is 392.10 g/mol.

Where can I buy thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate?

You can request a quote for thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate?

Yes, KEHONG BIO provides custom synthesis services for thymidine 5'-<(ethoxycarbonyl)-O-methyl>phosphonate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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