18,19-Dihydroxycorticosterone
TL;DR: 18,19-Dihydroxycorticosterone (CAS 115288-31-8) is a chemical compound with molecular formula C21H30O6 and molecular weight 378.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9S,10S,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-bis(hydroxymethyl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: 18,19-Dihydroxycorticosterone, 18,19-Dhco, Benzyl 3,4-diaminobenzoxylate, 11,18,19,21-Tetrahydroxypregn-4-ene-3,20-dione, 11beta,18,19,21-Tetrahydroxypregn-4-ene-3,20-dione
| Molecular Formula | C21H30O6 |
|---|---|
| Molecular Weight | 378.20 g/mol |
| LogP | -0.5 |
| Topological Polar Surface Area | 115.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 378.20422 |
| Heavy Atoms | 27 |
| Complexity | 672.0 |
Chemical Identifiers
| CAS Number | 115288-31-8 |
|---|---|
| SMILES | C1C[C@@H]([C@@]2([C@@H]1[C@@H]3CCC4=CC(=O)CC[C@@]4([C@H]3[C@H](C2)O)CO)CO)C(=O)CO |
| InChIKey | LRKLVKDUKYGITM-PUGGLORVSA-N |
Product Overview
18,19-Dihydroxycorticosterone (CAS 115288-31-8), with molecular formula C21H30O6 and molecular weight 378.20 g/mol. IUPAC: (8S,9S,10S,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-bis(hydroxymethyl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 18,19-Dihydroxycorticosterone
Property Insights of 18,19-Dihydroxycorticosterone
The XLogP value of -0.5 indicates that 18,19-Dihydroxycorticosterone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 18,19-Dihydroxycorticosterone. Following Lipinski's Rule of Five, 18,19-Dihydroxycorticosterone has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 18,19-Dihydroxycorticosterone?
The CAS number of 18,19-Dihydroxycorticosterone is 115288-31-8.
What is the molecular formula of 18,19-Dihydroxycorticosterone?
The molecular formula of 18,19-Dihydroxycorticosterone is C21H30O6.
What is the molecular weight of 18,19-Dihydroxycorticosterone?
The molecular weight of 18,19-Dihydroxycorticosterone is 378.20 g/mol.
Where can I buy 18,19-Dihydroxycorticosterone?
You can request a quote for 18,19-Dihydroxycorticosterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 18,19-Dihydroxycorticosterone?
Yes, KEHONG BIO provides custom synthesis services for 18,19-Dihydroxycorticosterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.