Fluorohydrocortisone
TL;DR: Fluorohydrocortisone (CAS 115160-13-9) is a chemical compound with molecular formula C21H29FO5 and molecular weight 380.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: Fluorohydrocortisone, A-fluorocortisol, 6-alpha-Fluorhydrocortisone, 6I+/--Fluorocortisol, 6.alpha.-Fluorocortisol
| Molecular Formula | C21H29FO5 |
|---|---|
| Molecular Weight | 380.20 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 380.1999 |
| Heavy Atoms | 27 |
| Complexity | 719.0 |
Chemical Identifiers
| CAS Number | 115160-13-9 |
|---|---|
| SMILES | C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)F |
| InChIKey | MEZCUMCMVYZPAH-HVIRSNARSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Fluorohydrocortisone (CAS 115160-13-9), with molecular formula C21H29FO5 and molecular weight 380.20 g/mol. IUPAC: (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of Fluorohydrocortisone
Property Insights of Fluorohydrocortisone
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Fluorohydrocortisone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Fluorohydrocortisone. Following Lipinski's Rule of Five, Fluorohydrocortisone has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fluorohydrocortisone?
The CAS number of Fluorohydrocortisone is 115160-13-9.
What is the molecular formula of Fluorohydrocortisone?
The molecular formula of Fluorohydrocortisone is C21H29FO5.
What is the molecular weight of Fluorohydrocortisone?
The molecular weight of Fluorohydrocortisone is 380.20 g/mol.
Where can I buy Fluorohydrocortisone?
You can request a quote for Fluorohydrocortisone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fluorohydrocortisone?
Yes, KEHONG BIO provides custom synthesis services for Fluorohydrocortisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.