Ecteinascidin 745 structure

Ecteinascidin 745

TL;DR: Ecteinascidin 745 (CAS 114899-28-4) is a chemical compound with molecular formula C39H43N3O10S and molecular weight 745.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(1R,2R,3R,11S,14R,26R)-5,6'-dihydroxy-6,7'-dimethoxy-7,21,30-trimethyl-27-oxospiro[17,19,28-trioxa-24-thia-13,30-diazaheptacyclo[12.9.6.13,11.02,13.04,9.015,23.016,20]triaconta-4(9),5,7,15,20,22-hexaene-26,1'-3,4-dihydro-2H-isoquinoline]-22-yl] acetate

Also Known As: ecteinascidin 745

CAS: 114899-28-4
Molecular Formula C39H43N3O10S
Molecular Weight 745.27 g/mol
LogP 4.09484
Topological Polar Surface Area 148.49 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 14
Rotatable Bonds 3
Exact Mass 745.2669
Heavy Atoms 53
Complexity 2091.067

Chemical Identifiers

CAS Number 114899-28-4
SMILES CC1=CC2=C([C@@H]3[C@@H]4[C@H]5C6=C(C(=C7C(=C6[C@@H](N4C[C@H](C2)N3C)COC(=O)[C@@]8(CS5)C9=CC(=C(C=C9CCN8)O)OC)OCO7)C)OC(=O)C)C(=C1OC)O

Product Overview

Ecteinascidin 745 (CAS 114899-28-4), with molecular formula C39H43N3O10S and molecular weight 745.27 g/mol. IUPAC: [(1R,2R,3R,11S,14R,26R)-5,6'-dihydroxy-6,7'-dimethoxy-7,21,30-trimethyl-27-oxospiro[17,19,28-trioxa-24-thia-13,30-diazaheptacyclo[12.9.6.13,11.02,13.04,9.015,23.016,20]triaconta-4(9),5,7,15,20,22-hexaene-26,1'-3,4-dihydro-2H-isoquinoline]-22-yl] acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ecteinascidin 745

XLogP
4.09484
TPSA (Topological Polar Surface Area)
148.49
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
14
Rotatable Bonds
3
Heavy Atoms
53
Complexity
2091.067
Exact Mass
745.2669
Monoisotopic Mass
745.2669
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ecteinascidin 745

The XLogP value of 4.09484 indicates that Ecteinascidin 745 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 148.49 Ų indicates high polarity, suggesting Ecteinascidin 745 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Ecteinascidin 745 has 3 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ecteinascidin 745?

The CAS number of Ecteinascidin 745 is 114899-28-4.

What is the molecular formula of Ecteinascidin 745?

The molecular formula of Ecteinascidin 745 is C39H43N3O10S.

What is the molecular weight of Ecteinascidin 745?

The molecular weight of Ecteinascidin 745 is 745.27 g/mol.

Where can I buy Ecteinascidin 745?

You can request a quote for Ecteinascidin 745 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ecteinascidin 745?

Yes, KEHONG BIO provides custom synthesis services for Ecteinascidin 745 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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