Losartan carboxaldehyde
TL;DR: Losartan carboxaldehyde (CAS 114798-36-6) is a chemical compound with molecular formula C22H21ClN6O and molecular weight 420.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde
Also Known As: Losartan Carboxaldehyde, Losartan EP Impurity K, losartancarbaldehyde, EXP 3179, Losartan Related Compound C
| Molecular Formula | C22H21ClN6O |
|---|---|
| Molecular Weight | 420.15 g/mol |
| LogP | 4.587 |
| Topological Polar Surface Area | 89.35 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 420.14655 |
| Heavy Atoms | 30 |
| Complexity | 1135.1615 |
Chemical Identifiers
| CAS Number | 114798-36-6 |
|---|---|
| SMILES | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C=O)Cl |
Product Overview
Losartan carboxaldehyde (CAS 114798-36-6), with molecular formula C22H21ClN6O and molecular weight 420.15 g/mol. IUPAC: 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde.
Chemical Property Profile of Losartan carboxaldehyde
Property Insights of Losartan carboxaldehyde
The XLogP value of 4.587 indicates that Losartan carboxaldehyde is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 89.35 Ų falls within the moderate polarity range, balancing permeability and solubility for Losartan carboxaldehyde. Following Lipinski's Rule of Five, Losartan carboxaldehyde has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losartan carboxaldehyde?
The CAS number of Losartan carboxaldehyde is 114798-36-6.
What is the molecular formula of Losartan carboxaldehyde?
The molecular formula of Losartan carboxaldehyde is C22H21ClN6O.
What is the molecular weight of Losartan carboxaldehyde?
The molecular weight of Losartan carboxaldehyde is 420.15 g/mol.
Where can I buy Losartan carboxaldehyde?
You can request a quote for Losartan carboxaldehyde directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losartan carboxaldehyde?
Yes, KEHONG BIO provides custom synthesis services for Losartan carboxaldehyde and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.