Aconityldoxorubicin structure

Aconityldoxorubicin

TL;DR: Aconityldoxorubicin (CAS 114390-31-7) is a chemical compound with molecular formula C33H33NO16 and molecular weight 699.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2Z)-2-[2-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-2-oxoethylidene]butanedioic acid

Also Known As: Aconityldoxorubicin, CA-Dxr, J1.629.626K, J3.137.448K, (2Z)-2-[2-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-2-oxoethylidene]butanedioic acid

CAS: 114390-31-7
Molecular Formula C33H33NO16
Molecular Weight 699.18 g/mol
LogP -0.3555
Topological Polar Surface Area 283.75 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 14
Rotatable Bonds 10
Exact Mass 699.17993
Heavy Atoms 50
Complexity 1848.9233

Chemical Identifiers

CAS Number 114390-31-7
SMILES C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)/C=C(/CC(=O)O)\C(=O)O)O

Product Overview

Aconityldoxorubicin (CAS 114390-31-7), with molecular formula C33H33NO16 and molecular weight 699.18 g/mol. IUPAC: (2Z)-2-[2-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-2-oxoethylidene]butanedioic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Aconityldoxorubicin

XLogP
-0.3555
TPSA (Topological Polar Surface Area)
283.75
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
14
Rotatable Bonds
10
Heavy Atoms
50
Complexity
1848.9233
Exact Mass
699.17993
Monoisotopic Mass
699.17993
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Aconityldoxorubicin

The XLogP value of -0.3555 indicates that Aconityldoxorubicin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 283.75 Ų indicates high polarity, suggesting Aconityldoxorubicin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Aconityldoxorubicin has 8 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Aconityldoxorubicin?

The CAS number of Aconityldoxorubicin is 114390-31-7.

What is the molecular formula of Aconityldoxorubicin?

The molecular formula of Aconityldoxorubicin is C33H33NO16.

What is the molecular weight of Aconityldoxorubicin?

The molecular weight of Aconityldoxorubicin is 699.18 g/mol.

Where can I buy Aconityldoxorubicin?

You can request a quote for Aconityldoxorubicin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Aconityldoxorubicin?

Yes, KEHONG BIO provides custom synthesis services for Aconityldoxorubicin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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