L-Tyrosyl-L-prolyl-L-leucyl-glycinamide
TL;DR: L-Tyrosyl-L-prolyl-L-leucyl-glycinamide (CAS 114216-64-7) is a chemical compound with molecular formula C22H33N5O5 and molecular weight 447.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Also Known As: Tyr-pro-leu-gly-NH2, Tyr-Pro-Leu-Gly amide, [Tyr6]-Oxytocin fragment 6-9, Glycinamide,D-tyrosyl-L-prolyl-L-leucyl, Glycinamide, D-tyrosyl-L-prolyl-L-leucyl-
| Molecular Formula | C22H33N5O5 |
|---|---|
| Molecular Weight | 447.25 g/mol |
| LogP | -0.6146 |
| Topological Polar Surface Area | 167.85 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 10 |
| Exact Mass | 447.24817 |
| Heavy Atoms | 32 |
| Complexity | 826.5054 |
Chemical Identifiers
| CAS Number | 114216-64-7 |
|---|---|
| SMILES | CC(C)CC(C(=O)NCC(=O)N)NC(=O)C1CCCN1C(=O)C(CC2=CC=C(C=C2)O)N |
Product Overview
L-Tyrosyl-L-prolyl-L-leucyl-glycinamide (CAS 114216-64-7), with molecular formula C22H33N5O5 and molecular weight 447.25 g/mol. IUPAC: 1-[2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide.
Chemical Property Profile of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide
Property Insights of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide
The XLogP value of -0.6146 indicates that L-Tyrosyl-L-prolyl-L-leucyl-glycinamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 167.85 Ų indicates high polarity, suggesting L-Tyrosyl-L-prolyl-L-leucyl-glycinamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, L-Tyrosyl-L-prolyl-L-leucyl-glycinamide has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide?
The CAS number of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide is 114216-64-7.
What is the molecular formula of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide?
The molecular formula of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide is C22H33N5O5.
What is the molecular weight of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide?
The molecular weight of L-Tyrosyl-L-prolyl-L-leucyl-glycinamide is 447.25 g/mol.
Where can I buy L-Tyrosyl-L-prolyl-L-leucyl-glycinamide?
You can request a quote for L-Tyrosyl-L-prolyl-L-leucyl-glycinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L-Tyrosyl-L-prolyl-L-leucyl-glycinamide?
Yes, KEHONG BIO provides custom synthesis services for L-Tyrosyl-L-prolyl-L-leucyl-glycinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.