Bortezomib, (1S,2R)-
TL;DR: Bortezomib, (1S,2R)- (CAS 1132709-16-0) is a chemical compound with molecular formula C19H25BN4O4 and molecular weight 384.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(1S)-3-methyl-1-[[(2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
Also Known As: Bortezomib, Velcade, (1S,2R)-Bortezomib, Bortezomib Impurity 5, Velcade(Bortezomib)
| Molecular Formula | C19H25BN4O4 |
|---|---|
| Molecular Weight | 384.20 g/mol |
| LogP | 0.36 |
| Topological Polar Surface Area | 124.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 384.1969 |
| Heavy Atoms | 28 |
| Complexity | 500.0 |
Chemical Identifiers
| CAS Number | 1132709-16-0 |
|---|---|
| SMILES | B([C@@H](CC(C)C)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
| InChIKey | GXJABQQUPOEUTA-NVXWUHKLSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Bortezomib, (1S,2R)- (CAS 1132709-16-0), with molecular formula C19H25BN4O4 and molecular weight 384.20 g/mol. IUPAC: [(1S)-3-methyl-1-[[(2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid.
Chemical Property Profile of Bortezomib, (1S,2R)-
Property Insights of Bortezomib, (1S,2R)-
The XLogP value of 0.36 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bortezomib, (1S,2R)-. The TPSA of 124.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Bortezomib, (1S,2R)-. Following Lipinski's Rule of Five, Bortezomib, (1S,2R)- has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bortezomib, (1S,2R)-?
The CAS number of Bortezomib, (1S,2R)- is 1132709-16-0.
What is the molecular formula of Bortezomib, (1S,2R)-?
The molecular formula of Bortezomib, (1S,2R)- is C19H25BN4O4.
What is the molecular weight of Bortezomib, (1S,2R)-?
The molecular weight of Bortezomib, (1S,2R)- is 384.20 g/mol.
Where can I buy Bortezomib, (1S,2R)-?
You can request a quote for Bortezomib, (1S,2R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bortezomib, (1S,2R)-?
Yes, KEHONG BIO provides custom synthesis services for Bortezomib, (1S,2R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.