Imipramine Hydrochloride
TL;DR: Imipramine Hydrochloride (CAS 113-52-0) is a chemical compound with molecular formula C19H25ClN2 and molecular weight 316.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride
Also Known As: Imipramine hydrochloride, Imipramine Hcl, Tofranil, Pryleugan, Chrytemin
| Molecular Formula | C19H25ClN2 |
|---|---|
| Molecular Weight | 316.17 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 6.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 316.17062 |
| Heavy Atoms | 22 |
| Complexity | 291.0 |
| Solubility | >47.5 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 113-52-0 |
|---|---|
| SMILES | CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
| InChIKey | XZZXIYZZBJDEEP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Imipramine Hydrochloride (CAS 113-52-0), with molecular formula C19H25ClN2 and molecular weight 316.17 g/mol. IUPAC: 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride.
Chemical Property Profile of Imipramine Hydrochloride
Property Insights of Imipramine Hydrochloride
The XLogP value of 4.3 indicates that Imipramine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Imipramine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Imipramine Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Imipramine Hydrochloride?
The CAS number of Imipramine Hydrochloride is 113-52-0.
What is the molecular formula of Imipramine Hydrochloride?
The molecular formula of Imipramine Hydrochloride is C19H25ClN2.
What is the molecular weight of Imipramine Hydrochloride?
The molecular weight of Imipramine Hydrochloride is 316.17 g/mol.
Where can I buy Imipramine Hydrochloride?
You can request a quote for Imipramine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Imipramine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Imipramine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.