RefChem:237134
TL;DR: RefChem:237134 (CAS 112634-54-5) is a chemical compound with molecular formula C18H17ClFN3O and molecular weight 345.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1,4-benzodiazepin-2-yl]acetamide
Also Known As: 2,3-Dihydro-7-chloro-5-(2-fluorophenyl)-N-methyl-1H-1,4-benzodiazepine-2-acetamide, 1H-1,4-Benzodiazepine-2-acetamide, 2,3-dihydro-7-chloro-5-(2-fluorophenyl)-N-methyl-, 2-[7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1,4-benzodiazepin-2-yl]acetamide, [7-Chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]ethanimidic acid, 2-[7-Chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]ethanimidic acid
| Molecular Formula | C18H17ClFN3O |
|---|---|
| Molecular Weight | 345.10 g/mol |
| LogP | 3.0103 |
| Topological Polar Surface Area | 58.69 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 345.10443 |
| Heavy Atoms | 24 |
| Complexity | 821.6612 |
Chemical Identifiers
| CAS Number | 112634-54-5 |
|---|---|
| SMILES | CN1C(CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F)CC(=O)N |
Product Overview
RefChem:237134 (CAS 112634-54-5), with molecular formula C18H17ClFN3O and molecular weight 345.10 g/mol. IUPAC: 2-[7-chloro-5-(2-fluorophenyl)-1-methyl-2,3-dihydro-1,4-benzodiazepin-2-yl]acetamide.
Chemical Property Profile of RefChem:237134
Property Insights of RefChem:237134
The XLogP value of 3.0103 indicates that RefChem:237134 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.69 Ų, RefChem:237134 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:237134 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:237134?
The CAS number of RefChem:237134 is 112634-54-5.
What is the molecular formula of RefChem:237134?
The molecular formula of RefChem:237134 is C18H17ClFN3O.
What is the molecular weight of RefChem:237134?
The molecular weight of RefChem:237134 is 345.10 g/mol.
Where can I buy RefChem:237134?
You can request a quote for RefChem:237134 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:237134?
Yes, KEHONG BIO provides custom synthesis services for RefChem:237134 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.