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6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one
TL;DR: 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one (CAS 112523-34-9) is a chemical compound with molecular formula C6H3ClN2OS and molecular weight 185.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-1H-[1,3]thiazolo[5,4-b]pyridin-2-one
Also Known As: 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one, 2187AA, 6-chloro-1H-[1,3]thiazolo[5,4-b]pyridin-2-one, 6-chloro-2-oxo-1,2-dihydrothiazolo[5,4-b]pyridine, 6-chloro-2-oxo-1,2-dihydrothiazolo[5.4-b]pyridine
| Molecular Formula | C6H3ClN2OS |
|---|---|
| Molecular Weight | 185.97 g/mol |
| LogP | 1.638 |
| Topological Polar Surface Area | 45.75 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 185.96545 |
| Heavy Atoms | 11 |
| Complexity | 447.02417 |
Chemical Identifiers
| CAS Number | 112523-34-9 |
|---|---|
| SMILES | C1=C(C=NC2=C1NC(=O)S2)Cl |
Product Overview
6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one (CAS 112523-34-9), with molecular formula C6H3ClN2OS and molecular weight 185.97 g/mol. IUPAC: 6-chloro-1H-[1,3]thiazolo[5,4-b]pyridin-2-one.
Chemical Property Profile of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one
Property Insights of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one
The XLogP value of 1.638 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one. With a topological polar surface area (TPSA) of 45.75 Ų, 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one?
The CAS number of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one is 112523-34-9.
What is the molecular formula of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one?
The molecular formula of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one is C6H3ClN2OS.
What is the molecular weight of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one?
The molecular weight of 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one is 185.97 g/mol.
Where can I buy 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one?
You can request a quote for 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 6-Chlorothiazolo[5,4-b]pyridin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.