Spiguetine structure

Spiguetine

TL;DR: Spiguetine (CAS 112494-56-1) is a chemical compound with molecular formula C19H18N2O3 and molecular weight 322.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

17-methoxy-11-methyl-3,5-dioxa-11,13-diazapentacyclo[10.8.1.02,6.08,21.015,20]henicosa-1(21),2(6),7,13,15(20),16,18-heptaene

Also Known As: Spiguetine, 11-Methoxy-7-methyl-5,6,7,7a-tetrahydro-2H-[1,3]dioxolo[6,7]isoquinolino[1,8-cd][2]benzazepine, RefChem:380809

CAS: 112494-56-1
Molecular Formula C19H18N2O3
Molecular Weight 322.13 g/mol
LogP 2.6
Topological Polar Surface Area 43.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 1
Exact Mass 322.13174
Heavy Atoms 24
Complexity 513.0

Chemical Identifiers

CAS Number 112494-56-1
SMILES CN1CCC2=CC3=C(C4=C2C1N=CC5=C4C=CC(=C5)OC)OCO3
InChIKey LBQHMFHBCMWQAG-UHFFFAOYSA-N

Product Overview

Spiguetine (CAS 112494-56-1), with molecular formula C19H18N2O3 and molecular weight 322.13 g/mol. IUPAC: 17-methoxy-11-methyl-3,5-dioxa-11,13-diazapentacyclo[10.8.1.02,6.08,21.015,20]henicosa-1(21),2(6),7,13,15(20),16,18-heptaene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Spiguetine

XLogP
2.6
TPSA (Topological Polar Surface Area)
43.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
1
Heavy Atoms
24
Complexity
513.0
Exact Mass
322.13174
Monoisotopic Mass
322.13174
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Spiguetine

The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Spiguetine. With a topological polar surface area (TPSA) of 43.3 Ų, Spiguetine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Spiguetine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Spiguetine?

The CAS number of Spiguetine is 112494-56-1.

What is the molecular formula of Spiguetine?

The molecular formula of Spiguetine is C19H18N2O3.

What is the molecular weight of Spiguetine?

The molecular weight of Spiguetine is 322.13 g/mol.

Where can I buy Spiguetine?

You can request a quote for Spiguetine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Spiguetine?

Yes, KEHONG BIO provides custom synthesis services for Spiguetine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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