2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one
TL;DR: 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one (CAS 111865-34-0) is a chemical compound with molecular formula C14H8ClNO3 and molecular weight 273.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-2-(4-chlorophenyl)-4-(furan-2-ylmethylidene)-1,3-oxazol-5-one
Also Known As: BAS 00308580, 2-(4-Chloro-phenyl)-4-furan-2-ylmethylene-4H-oxazol-5-one, 2-(4-chlorophenyl)-4-(2-furylmethylene)-1,3-oxazolin-5-one, (E)-2-(4-chlorophenyl)-4-(furan-2-ylmethylene)oxazol-5(4H)-one, (4E)-2-(4-chlorophenyl)-4-(furan-2-ylmethylidene)-1,3-oxazol-5-one
| Molecular Formula | C14H8ClNO3 |
|---|---|
| Molecular Weight | 273.02 g/mol |
| LogP | 3.2775 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 273.01926 |
| Heavy Atoms | 19 |
| Complexity | 669.22644 |
Chemical Identifiers
| CAS Number | 111865-34-0 |
|---|---|
| SMILES | C1=COC(=C1)/C=C/2\C(=O)OC(=N2)C3=CC=C(C=C3)Cl |
Product Overview
2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one (CAS 111865-34-0), with molecular formula C14H8ClNO3 and molecular weight 273.02 g/mol. IUPAC: (4E)-2-(4-chlorophenyl)-4-(furan-2-ylmethylidene)-1,3-oxazol-5-one.
Chemical Property Profile of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one
Property Insights of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one
The XLogP value of 3.2775 indicates that 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one?
The CAS number of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one is 111865-34-0.
What is the molecular formula of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one?
The molecular formula of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one is C14H8ClNO3.
What is the molecular weight of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one?
The molecular weight of 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one is 273.02 g/mol.
Where can I buy 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one?
You can request a quote for 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-Chlorophenyl)-4-(2-furylmethylene)-1,3-oxazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.