20-Hydroxy-leukotriene E4
TL;DR: 20-Hydroxy-leukotriene E4 (CAS 111844-33-8) is a chemical compound with molecular formula C23H37NO6S and molecular weight 455.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5,20-dihydroxyicosa-7,9,11,14-tetraenoic acid
Also Known As: 20-Hydroxy-leukotriene E4, 20-OH-Leukotriene E4, 20-hydroxy-LTE4, 20-Hydroxyleukotriene E4, 2-oxo-4-hydroxyvalerate
| Molecular Formula | C23H37NO6S |
|---|---|
| Molecular Weight | 455.23 g/mol |
| LogP | 3.2835 |
| Topological Polar Surface Area | 141.08 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 19 |
| Exact Mass | 455.23416 |
| Heavy Atoms | 31 |
| Complexity | 602.87415 |
Chemical Identifiers
| CAS Number | 111844-33-8 |
|---|---|
| SMILES | C(CC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N)CCO |
Product Overview
20-Hydroxy-leukotriene E4 (CAS 111844-33-8), with molecular formula C23H37NO6S and molecular weight 455.23 g/mol. IUPAC: (5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5,20-dihydroxyicosa-7,9,11,14-tetraenoic acid.
Chemical Property Profile of 20-Hydroxy-leukotriene E4
Property Insights of 20-Hydroxy-leukotriene E4
The XLogP value of 3.2835 indicates that 20-Hydroxy-leukotriene E4 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 141.08 Ų indicates high polarity, suggesting 20-Hydroxy-leukotriene E4 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 20-Hydroxy-leukotriene E4 has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 20-Hydroxy-leukotriene E4?
The CAS number of 20-Hydroxy-leukotriene E4 is 111844-33-8.
What is the molecular formula of 20-Hydroxy-leukotriene E4?
The molecular formula of 20-Hydroxy-leukotriene E4 is C23H37NO6S.
What is the molecular weight of 20-Hydroxy-leukotriene E4?
The molecular weight of 20-Hydroxy-leukotriene E4 is 455.23 g/mol.
Where can I buy 20-Hydroxy-leukotriene E4?
You can request a quote for 20-Hydroxy-leukotriene E4 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 20-Hydroxy-leukotriene E4?
Yes, KEHONG BIO provides custom synthesis services for 20-Hydroxy-leukotriene E4 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.