氨柔比星
TL;DR: 氨柔比星 (CAS 110267-81-7) is a chemical compound with molecular formula C25H25NO9 and molecular weight 483.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氨柔比星
(9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
Also Known As: Amrubicin, AMR
| Molecular Formula | C25H25NO9 |
|---|---|
| Molecular Weight | 483.15 g/mol |
| LogP | 0.9 |
| Topological Polar Surface Area | 177.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 3 |
| Exact Mass | 483.15292 |
| Heavy Atoms | 35 |
| Complexity | 881.0 |
Chemical Identifiers
| CAS Number | 110267-81-7 |
|---|---|
| SMILES | CC(=O)[C@]1(CC(C2=C(C1)C(=C3C(=C2O)C(=O)C4=CC=CC=C4C3=O)O)O[C@H]5C[C@@H]([C@@H](CO5)O)O)N |
| InChIKey | VJZITPJGSQKZMX-WEIUFPNZSA-N |
Product Overview
氨柔比星 (CAS 110267-81-7), with molecular formula C25H25NO9 and molecular weight 483.15 g/mol. IUPAC: (9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione.
Chemical Property Profile of 氨柔比星
Property Insights of 氨柔比星
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 氨柔比星. The TPSA of 177.0 Ų indicates high polarity, suggesting 氨柔比星 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 氨柔比星 has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氨柔比星?
The CAS number of 氨柔比星 is 110267-81-7.
What is the molecular formula of 氨柔比星?
The molecular formula of 氨柔比星 is C25H25NO9.
What is the molecular weight of 氨柔比星?
The molecular weight of 氨柔比星 is 483.15 g/mol.
Where can I buy 氨柔比星?
You can request a quote for 氨柔比星 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氨柔比星?
Yes, KEHONG BIO provides custom synthesis services for 氨柔比星 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.