Tirilazad Mesylate structure

Tirilazad Mesylate

TL;DR: Tirilazad Mesylate (CAS 110101-67-2) is a chemical compound with molecular formula C39H56N6O5S and molecular weight 720.40 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,10S,13S,14S,16R,17S)-17-[2-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]acetyl]-10,13,16-trimethyl-6,7,8,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one;methanesulfonic acid

Also Known As: Tirilazad mesylate, Freedox, Tirilazad, Tirilazad mesilate, Freedox (TN)

CAS: 110101-67-2
Molecular Formula C39H56N6O5S
Molecular Weight 720.40 g/mol
LogP 4.96
Topological Polar Surface Area 136.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 11
Rotatable Bonds 6
Exact Mass 720.4033
Heavy Atoms 51
Complexity 1380.0

Chemical Identifiers

CAS Number 110101-67-2
SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@H]1C(=O)CN5CCN(CC5)C6=NC(=NC(=C6)N7CCCC7)N8CCCC8)C)C.CS(=O)(=O)O
InChIKey HPZOOQSXPMEJBV-ODCFVKFUSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (42 patents) Organic Building Blocks (2 patents) Pharmaceutical Intermediates (103 patents)

Product Overview

Tirilazad Mesylate (CAS 110101-67-2), with molecular formula C39H56N6O5S and molecular weight 720.40 g/mol. IUPAC: (8S,10S,13S,14S,16R,17S)-17-[2-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]acetyl]-10,13,16-trimethyl-6,7,8,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one;methanesulfonic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tirilazad Mesylate

XLogP
4.96
TPSA (Topological Polar Surface Area)
136.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
11
Rotatable Bonds
6
Heavy Atoms
51
Complexity
1380.0
Exact Mass
720.4033
Monoisotopic Mass
720.4033
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tirilazad Mesylate

The XLogP value of 4.96 indicates that Tirilazad Mesylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 136.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Tirilazad Mesylate. Following Lipinski's Rule of Five, Tirilazad Mesylate has 1 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tirilazad Mesylate?

The CAS number of Tirilazad Mesylate is 110101-67-2.

What is the molecular formula of Tirilazad Mesylate?

The molecular formula of Tirilazad Mesylate is C39H56N6O5S.

What is the molecular weight of Tirilazad Mesylate?

The molecular weight of Tirilazad Mesylate is 720.40 g/mol.

Where can I buy Tirilazad Mesylate?

You can request a quote for Tirilazad Mesylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tirilazad Mesylate?

Yes, KEHONG BIO provides custom synthesis services for Tirilazad Mesylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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