Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone
TL;DR: Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone (CAS 109377-04-0) is a chemical compound with molecular formula C25H31ClN4O5 and molecular weight 502.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-methylamino]acetyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide
Also Known As: DAMCK, DAMK, Tyr-ala-gly-mephe-cmk, Tyr-ala-gly-mephe chloromethyl ketone, Tyr-ala-gly-N(alpha)-mephe-chloromethyl ketone
| Molecular Formula | C25H31ClN4O5 |
|---|---|
| Molecular Weight | 502.20 g/mol |
| LogP | 0.7605 |
| Topological Polar Surface Area | 141.83 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 12 |
| Exact Mass | 502.1983 |
| Heavy Atoms | 35 |
| Complexity | 1016.27704 |
Chemical Identifiers
| CAS Number | 109377-04-0 |
|---|---|
| SMILES | C[C@H](C(=O)NC(=O)CN(C)[C@@H](CC1=CC=CC=C1)C(=O)CCl)NC(=O)[C@H](CC2=CC=C(C=C2)O)N |
Product Overview
Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone (CAS 109377-04-0), with molecular formula C25H31ClN4O5 and molecular weight 502.20 g/mol. IUPAC: (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-methylamino]acetyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide.
Chemical Property Profile of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone
Property Insights of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone
The XLogP value of 0.7605 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone. The TPSA of 141.83 Ų indicates high polarity, suggesting Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone?
The CAS number of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone is 109377-04-0.
What is the molecular formula of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone?
The molecular formula of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone is C25H31ClN4O5.
What is the molecular weight of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone?
The molecular weight of Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone is 502.20 g/mol.
Where can I buy Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone?
You can request a quote for Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone?
Yes, KEHONG BIO provides custom synthesis services for Tyrosyl-alanyl-glycyl-N(alpha)-methylphenylalanine chloromethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.